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Crown Publishing Group, Summer 2019

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Ticker
The Quest to Create an Artificial Heart
By (author): Mimi Swartz
9780804138024 Paperback, Trade English General Trade BIOGRAPHY & AUTOBIOGRAPHY / Science & Technology Sep 10, 2019
$23.00 CAD
Active 5.2 x 8 x 0.8 in | 0.58 lb 336 pages 1 8-PG 4C INSERT Crown Broadway Books
Now in paperback, Texas Monthly executive editor and two-time National Magazine Award winner Mimi Swartz takes readers behind the scenes of perhaps the greatest medical and technological quest of our time, as she follows pioneering heart surgeon O. H. “Bud” Frazier and his partner, Dr. Billy Cohn, in Frazier’s lifelong effort to develop, perfect, and successfully implant an artificial heart in patients whose hearts are failing.

Renowned journalist Mimi Swartz takes readers on an incredible behind-the-scenes journey into a heart surgeon’s epic quest to develop an artificial heart—a reliable, implantable device that would extend the lives of patients who have no other recourse. As director of cardiovascular surgery at the Texas Heart Institute, and arguably the foremost heart surgeon in the world, Bud Frazier’s lifelong mission, since his stint in the war in Vietnam, has been to save lives by creating an artificial heart for those whose hearts are failing. There are 50,000 people on the waiting list for a heart transplant at any given time, with fewer than 2,500 transplants performed each year.

Chronicling the evolution of cardiac medicine, from pioneering efforts in open heart surgery and bypass operations, under Michael DeBakey and Denton Cooley, to the advent of valve replacement and heart transplants, including protege Bud Frazier’s introduction of the Left Ventricular Assist Device (or LVAD) that Vice President Cheney used for a decade before his successful heart transplant, Swartz follows Frazier and his partner, Billy Cohn, as they feverishly design, develop, and test new heart designs. In a gripping narrative that takes readers from the operating theater to the basement of the famed Texas Heart Institute, where calves are implanted with the new heart devices and monitored meticulously, to the relentless quest for funding, as government research money dries up, Swartz has created an unputdownable narrative that weaves together science, research, technology, and the relentless obsession of a surgeon determined to extend patients’ lives.

EXPERT REPORTING: Based on three years of interviews and research

COMPELLING SETTING: Set at the Texas Heart Institute, one of the foremost cardiac research centers in the world

INTRIGUING NARRATIVE: Chronicles the story of an incredibly gifted heart surgeon, and his colorful partner, who has spent his career developing a working artificial heart

TIMELY TOPIC: Heart disease is the number one killer in the United States and around the world. Over 600,000 people in the United States succumb to the disease every year. Fifty thousand people are on the waiting list to receive a heart transplant, most with little hope of finding a donor heart.

MIMI SWARTZ is a long-time executive editor at Texas Monthly and a two-time National Magazine Award winner and four time finalist. She is the coauthor of the national bestseller Power Failure, with Sherron Watkins, about the failures at Enron. Her work has appeared in The New Yorker, Vanity Fair, Esquire, and Slate, and her op-ed pieces appear regularly in the New York Times.

Author Residence: Houston, TX

Publicity: National print attention

Author events and interviews out of Houston, TX

Amazon Editors’ “Best Books of the Month” Pick for August in History and Nonfiction

“It doesn’t take an acute interest in the human heart to be hooked after only a few pages of Ticker. And…how’s this for a reason to read it: heart disease, Swartz notes early on, is responsible for the largest number of deaths in the U.S. and worldwide.” 
-Vanity Fair

“Doctors and researchers have long recognized the need for an artificial organ, or…a machine of some kind that can assist a diseased heart until a transplant candidate can be found. The Holy Grail is a device that would make transplants altogether unnecessary.  The search for that grail has been, as Mimi Swartz shows in her fascinating book, as complicated as the essential organ itself. Ticker: The Quest to Create an Artificial Heart tells a story as big as Texas…“
-The Wall Street Journal

“A developing story about…innovation, daring, perceived double-crosses, competition and conflict…Ticker beats at an accelerated rate…Writer Jane Mayer compared it to The Right Stuff, with which it shares some commonalities: the tension of daredevilry in the name of research and development, and multiple characters who are brilliant, eccentric and driven.”
-The Houston Chronicle

“In bringing to life more than 70 years of medical history, Swartz often achieves a novelist’s level of telling detail, the kind that can only result from determined, painstaking reporting…Ticker makes achieving a truly viable version [of an artificial heart]…seem not just possible, but inevitable.”
-The Texas Observer

“Fast paced and meticulously researched.” 
-Houston CityBook

“A frequently hypnotic story…of the nexus between talent, institutional support, experimentation and money.”
-Austin American-Statesman

“[A] pacy, blow-by-blow account of the search for a viable artificial heart…Swartz offers a vivid gallery of the medical pioneers who have jostled for the prize.”
-Nature.com

Ticker is beautifully and ingeniously constructed, flowing like a fast-paced science-fiction novel, engendering wide-eyed wonder at a remarkable, smart, compelling, and very human story at the busy intersection of money, politics, law, science, medicine, ethics, and philosophy.”
-Lone Star Literary Review

“A riveting medical thriller…Told in an appropriately over-the-top style, this is a quintessentially Texas story: sprawling, unpredictable, and teeming with risk and opportunity.”
-Publishers Weekly

“Even casually interested readers will become fascinated by Swartz’s vivid depiction of Frazier at work in the operating room…Swartz is a witty, savvy, seasoned journalist, and she offers a welcome history of significant medical advances.”
-Kirkus Reviews

“Smart, compelling, and completely engaging, Ticker is a story about science, personality, innovation, and obsession, all in pursuit of a staggering accomplishment, the creation of an artificial heart. Mimi Swartz drives the narrative with great style and deep reporting; it’s a book anyone with a heart will love.”
-Susan Orlean, author of Rin Tin Tin: The Life and the Legend and The Orchid Thief
 
“A remarkable journey through the harrowing world of heart surgery, as a brilliantly gifted and eccentric team of doctors work to develop a complete artificial heart, to save the thousands of patients a year whose hearts are failing.”
 -Bryan Burrough, author of Public Enemies, The Big Rich and Barbarians at the Gate
 
Ticker is like a medical version of Tom Wolfe’s The Right Stuff. Swartz takes you into the operating theater with some of the most brilliant, ingenious and driven heart specialists in the world. It’s a book full of memorable characters grappling with life-threatening crises, which is both illuminating about modern medicine, and also just a wonderful read.”
-Jane Mayer, author of Dark Money
 
Ticker is a page-turner, a mind-expander, a heart-pounder.  Swartz unveils a wild story of medical innovation with the keen eye of a storyteller.”
-David Eagleman, Stanford University neuroscientist and internationally bestselling author of The Brain and Incognito
 
“A fast paced, utterly riveting tale of the decades of effort that have gone into developing an artificial heart. The characters, many of whom dedicated their lives to this quest, are captivating, and their rivalries are the stuff of legend.”
-Bethany McLean, co-author of All the Devils Are Here and The Smartest Guys in the Room
 
“A thrilling and affecting account of a modern medical miracle. Ticker is not only an inspiring tale of persistence, imagination, and sacrifice, it’s also a joy to read.”
-Lawrence Wright, Pulitzer Prize winning author of The Looming Tower and God Save Texas
 
“Who knew that the story of the artificial heart was such a rip-roaring one, with one larger-than-life character after another, and plot twists galore?  In Ticker, Mimi Swartz has told that story with verve and elegance, and brought those characters to vivid life. A wonderful work of nonfiction by a wonderful nonfiction writer.”
-Joe Nocera, Bloomberg News columnist and author of Indentured: The Inside Story of the Rebellion Against the NCAA
 
“An exciting, propulsive, and at times surprisingly tender account of the swashbuckling surgeons and inventive geniuses who achieved one of the greatest medical breakthroughs—the development of the artificial heart. Mimi Swartz has done an outstanding job, and uncovered the human story behind the triumph of technology.”
 -Jennet Conant, New York Times bestselling author of Tuxedo Park and 109 East Palace

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